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. 2013 Nov 26;14(12):23330–23340. doi: 10.3390/ijms141223330

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© 2013 by the authors; licensee MDPI, Basel, Switzerland

This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).

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Figure 1. — CaBP-9k of transcellular calcium transport in duodenal enterocyte. In the transportation, calcium binds to membrane bound TRPV6, which influxes from the extracellular environment. The calcium translocates into the cytoplasm and binds to calcium binding protein CaBP-9k. The calcium-bound CaBP-9k may also move to the basolateral side and transfer its bound calcium to PMCA1b or NCX channel protein, leading to uptake into serum.