Table 2.
Correlation coefficient, rate constant, and half-time obtained by fitting the release data of prindopril erbumine (PE) from iron oxide nanoparticles coated with chitosan-prindopril erbumine (FCPE) into phosphate-buffered solution at pH 7.4 and 4.8.
Aqueous Solution | Saturated Release (%) | R2 | Rate constant (k) a (mg/min) | t1/2a (min) | ||
---|---|---|---|---|---|---|
| ||||||
First-order | Pseudo-second order | Parabolic diffusion | ||||
pH 7.4 | 85.8 | 0.9582 | 0.4776 | 0.9054 | 2.02 × 10−4 | 3431 |
pH 4.8 | 72.2 | 0.8334 | 0.6760 | 0.7367 | 1.4 × 10−3 | 495 |
Estimated using first order kinetics.