TABLE 1.

Results of replicate tests in eight laboratories using 1-μg voriconazole disks in prepared MH-GMB plates and MHA plates flooded with GMB^a

^aMHA was supplemented by adding GMB before autoclaving (prepared agar) or by flooding MHA plates with GMB solution the day before testing (flooded agar).

^bHorizontal broken lines designate the QC limits for tests with each control strain, and brackets designate the median zone diameter for each data set. The QC limits were 16 to 25 mm for C. krusei ATCC 6258, 28 to 37 mm for C. parapsilosis ATCC 22019, and 31 to 42 mm for C. albicans ATCC 90028. For C. parapsilosis, of the 19 zones with diameters of <28 mm, 18 were reported by laboratory 1, and the 29 zones with diameters of >37 mm were reported by a variety of laboratories. For C. albicans, of the 26 zones with diameters of <31 mm, 22 were reported by laboratory 6, and of the 23 zones with diameters of >42 mm, 18 were reported by laboratory 3. With these QC limits, 96.8, 94.8, and 94.8% of the total number of zones examined for C. krusei, C. parapsilosis, and C. albicans, respectively, were included.