Table 5.
Formulae Designation of CCMS Core Tablets.
| Excipients | Formulae | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
|
| ||||||||||
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | ||
| Drug | CCMS (mg) | 400 | 400 | 400 | 400 | 400 | 400 | 400 | 400 | 400 |
|
| ||||||||||
| Binders | Carboxymethylcellulose Sodium (Right amount, w/v) | 5% | 3% | 7% | 3% | 3% | 3% | 3% | 3% | |
| HPMC (Right amount, w/v) | - | 5% | - | - | - | - | - | - | - | |
|
| ||||||||||
| Lubricants | Magnesium Stearate (mg) | 4 | 4 | 4 | 4 | - | 4 | 4 | 4 | 4 |
| SLS (mg) | - | - | - | - | 4 | - | - | - | - | |
|
| ||||||||||
| Disintegrants | Sodium Starch Glycolate (mg) | - | - | - | - | - | 24 | - | 16 | 32 |
| Croscarmellose Sodium (mg) | - | - | - | - | - | - | 24 | - | - | |
Notes: Percentage is expressing concentration in tablet. Abbreviations: CCMS, capsaicin-chitosan microspheres; HPMC, hydroxypropyl methylcellulose.