Figure 1.

Histological evaluation of atorvastatin on bleomycin-induced lung in rats. (A) Lung tissue sections of control animals showing normal lung morphologies: thin lined interalveolar septa with well organized alveolar space; (B) Lung tissue sections of bleomycin-induced animals showing distorted lung morphologies: collapsed alveolar spaces with inflammatory exudates, wider and thickened interalveolar septa; (C) Lung tissue section of atorvastatin treated animals: lower inflammatory infiltrates with lessened alveolar thickening; and (D) Lung tissue section of atorvastatin alone administered animals showing similar morphology with that of control animals. Representative histological section of the lungs was stained by hematoxylin and eosin (×400).