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. 2013 Dec 9;110(52):21048–21053. doi: 10.1073/pnas.1319097110

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Fig. 2. — Live cell imaging of centromeres and telomeres by TALEColor. U2OS cells were cotransfected for 24 h with TALEmCherry-TelR20 to label telomeres together with one of three TALEs designed to recognize centromeric repeats. (Top row) TALEVenus-PanCen, a TALE predicted to bind all human centromeres. (Middle row) TALEVenus-Cen18, specific for an α-satellite higher order repeat on chromosome 18 (D18Z1). (Bottom row) TALEVenus-Cen15, a specific α-satellite higher order repeat on chromosome 15 (D15Z3). Overlay images are shown in the Far Right column. (Scale bar, 5 μm.)