Table 4.
Clinical Trial Statistics for Nighttime (10:00 pm-7:00 am)a
| Subject | 3 | 8 | 10 | 11 | Mean ± standard deviation |
| Age (years) | 56 | 28 | 44 | 55 | |
| Gender | Male | Female | Female | Female | |
| Years with T1DM | 43 | 7 | 34 | 17 | |
| Weight (kg) | 95.5 | 66.9 | 75.9 | 61.4 | |
| 97.7 | 66.5 | 75.9 | 61.4 | ||
| Total daily insulin uTDI (U) | 41.2 | 36.6 | 32 | 26.1 | |
| 45.1 | 34.4 | 31 | 31.6 | ||
| Insulin delivered (U) | 8.4 | 4.8 | 3.6 | 4 | 5.20 ± 2.2 |
| 9.55 | 6.6 | 4.45 | 6.45 | 6.76 ± 2.1 | |
| Insulin above basal (U) | -1 | -1.03 | -0.7 | -2.2 | -1.23 ± 0.7 |
| 0.15 | 0.55 | 0.57 | -0.05 | 0.31 ± 0.3 | |
| Mean CGM (mg/dl) | 125 | 149 | 131 | 109 | 129 ± 17 |
| 148 | 147 | 137 | 119 | 138 ± 14 | |
| Mean YSI (mg/dl) | 117 | 146 | 149 | 103 | 129 ± 22 |
| 150 | 127 | 143 | 128 | 137 ± 11 | |
| Breakfast (7:00 am) blood glucose (mg/dl) | 93 | 154 | 121 | 118 | 121 ± 25 |
| 84 | 116 | 129 | 138 | 117 ± 24 | |
| Hypoglycemia alarms with 16 gCHO treatments | 3 | 2 | 0 | 2 | |
| 3 | 0 | 1 | 2 | ||
| CGM time in range 80–140 mg/dl (%) | 81 | 29 | 39 | 79 | 56.8 ± 26.8 |
| 47 | 46 | 42 | 85 | 55.0 ± 20.1 | |
| CGM time in range 70–80 mg/dl (%) | 100 | 81 | 100 | 87 | 91.9 ± 9.6 |
| 64 | 86 | 100 | 100 | 87.6 ± 16.8 |
a
Here PZMPC is contrasted with invariant-zone-MPC. There are no clinical results for the nighttime-basal strategy. The top rows (shaded) of double–row entries correspond to PZMPC and the bottom row to invariant-zone-MPC.