Table 1.
Variables | Glargine | Total: Detemir | NPH insulin | Glargine | BOT: Detemir | NPH insulin | Glargine | ICT: Detemir | NPH insulin |
N | 4211 | 1290 | 3876 | 2247 | 490 | 1331 | 1964 | 800 | 2545 |
Age (years) | 70.2 (11.3)a,b | 66.7 (11.7)a | 69.0 (10.9)b | 71.1 (11.3)a,a | 6 7.1 ( 11. 7 ) a | 6 9 . 6 (11. 2) b | 68.4 (11.0)a | 6 5 .7 (11. 4 ) a | 68.5 (10.8) |
Males (%) | 51.6 | 51.1 | 52.1 | 51.4 | 49.3 | 53.0 | 51.7 | 52.2 | 51.9 |
Private health insurance (%) | 4.9b | 5.4 | 2.9b | 5.7b | 6.5 | 3.0b | 4 .1b | 4.7 | 2.9b |
Diabetologist treatment (%) | 17. 0 b | 16.9 | 26.5b | 11. 2 b | 12.0 | 20.0b | 24.6b | 20.6 | 30.3b |
Region (West Germany) (%) | 61.9a,b | 65.5a | 62.7b | 66.8 | 68.6 | 69.5 | 56.6a | 64.2a | 58.7 |
Urban residencyc (%) | 24.4a,b | 2 1.1 a | 22.3b | 26.3b | 25.6 | 23.0b | 2 2.1a | 18 .1a | 21.7 |
Charlson comorbidity score | 2.3 (1.6) | 2.3 (1.5) | 2.3 (1.5) | 2.1 (1.6) | 2.2 (1.6) | 2.1 (1.4) | 2.4 (1.6) | 2.4 (1.4) | 2.3 (1.5) |
Daily insulin dosage (IU) | 22.7 (14.0)a,b | 26.0 (17.0)a | 24.3 (15.9)b | 20.5 (13.0)a | 22.7 (14.8)a | 21.6 (14.9) | 25.9 (14.7 )a | 28.5 (18.2)a | 25.8 (16.1) |
HbA1c (%) d | 7. 8 (1. 3 ) a | 8 .1 (1. 4) a | 7.9 (1.3) | 7. 9 (1. 3 ) a | 7. 8 (1. 2) a | 7.8 (1.2) | 7. 9 (1. 3) a | 8.2 (1.5)a | 7.9 (1.4) |
BMI (kg/m2)e | 31.1 ( 5 .6 ) b | 31.8 (5.9) | 32.0 (5.6)b | 30.9 (5.5) | 31.6 (5.5) | 31.6 (5.5) | 31.4 (5.6)b | 32.5 (5.9) | 32.3 (5.7)b |
p < .05 glargine versus detemir.
p < .05 glargine versus NPH.
>100,000 inhabitants.
Recorded values: glargine n = 2858, detemir n = 937, NPH n = 2651.
Recorded values: glargine n = 1177, detemir n = 381, NPH n = 11 9 3 .