Table 2.
Crude Analysis of Maternal Risk Factors for Schizencephaly.
| Cases, % (n = 46)a |
NVSR controls, % (n = 4 021 726) |
P | |
|---|---|---|---|
| Ethnicity (% white) | 70.8 | 78.9 | .1684 |
| Maternal education (% college or higher) | 16.7 | 25.5 | .1590 |
| Maternal age (% <20 y) | 43.8 | 10.8 | <.0001*** |
| Smoking (% smoker)b | 22.9 | 11.4 | .0121 |
| Alcohol (% drinking)b | 20.8 | 0.8 | <.0001*** |
| Prenatal care (% with first trimester care) | 45.8 | 83.7 | <.0001*** |
| Drug use (any type)c | 11.6 | 5.6 | .1642 |
Abbreviation: NVSR, National Vital Statistics Report.
a
Cases exclude those for whom information on 2 mothers was unavailable.
b
Tobacco use and alcohol use excludes California births which did not require reporting on birth certificates.
c
The control sample for drug use was from 2002 National Survey on Drug Use and Health.
***
P < 0.0001.