Table 1.
Linkage disequilibrium of three loci in TP53BP1
| K1136* | G412S* | |||||
|---|---|---|---|---|---|---|
| D353E* | Homozygous WT |
Heterozygous | Homozygous variant |
Homo WT |
Heterozygous | Homozygous variant |
| Homozygous WT | 49 | 2 | 1 | 50 | 2 | 0 |
| Heterozygous | 3 | 60 | 1 | 29 | 25 | 0 |
| Homozygous variant | 0 | 3 | 40 | 6 | 16 | 21 |
Abbreviation: WT = wild type.
Correlation between allele status of all three loci was highly significant at p < 0.00001.