FIG. 4.

AMP induces transmembrane currents in oocytes expressing the LdNT1.2 nucleoside transporter. Two-electrode voltage clamp experiments were performed on LdNT1.2-expressing oocytes essentially as described for Fig. 3. (A) Current-voltage curves demonstrating that increasing concentrations of AMP (300 nM to 100 μM) induce increasing inward-directed currents. (B) AMP-induced currents saturated with increasing AMP concentrations. Reproduced from reference 46 with permission of the publisher.