Table 4.

Results of kinetic studies conducted on vagino-adhesive propranolol HCl gel formulations F3, F8, F13 and F17, based on various mathematical models fitted.

Formulation code	Zero order		First order		Higuchi		Korsemeyer-Peppas
	K 0 (h -1 )	R 2	K 1 (h -1 )	R 2	K H (h -1/2 )	R 2	Release exponent (n)	R 2
F 3	10.724	0.7995	0.470	0.9871	35.536	0.9704	0.597	0.9967
F 8	11.029	0.8564	0.380	0.9972	35.586	0.9856	0.614	0.9950
F 13	6.700	0.9107	0.180	0.9478	26.180	0.9955	0.562	0.9927
F 17	10.360	0.8044	0.340	0.9895	34.241	0.9712	0.566	0.9849