Table 3.
Resistance or combined exercise and insulin resistance (nonrandomized controlled trials).
| References | Gender | Age | Treatment | BW (kg) |
BMI (kg/m2) |
IS | Study Duration |
Protocol | ΔBW (kg) |
ΔBMI (kg/m2) |
ΔIS (%) |
IS Measure |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Treuth et al. [46] | 22 girls | 7–10 | Control (lean) exercise |
29.1 46.6 |
NA | NA 315.9 |
5 mo | 3 days/wk, 50% of 1RM 2 sets, 12–15 reps, 7 exercises |
2.9* 4.0* |
NA | NA −8.2 |
Insulin AUC (OGTT) (pmol/L) |
|
| ||||||||||||
| Bell et al. [47] |
8 boys 6 girls |
12.7 | Exercise | 80.6 | 31.6 | 8.2 | 8 wk | 3 days/wk, 60 min/session Strength exercise (2 sets, 10 exercises, 55–65% of 1RM) + Aerobic exercise (cycling) |
0.6 | −0.4 | 22.2* | Euglycemic clamp M(lbm) (mg/kg/min) |
|
| ||||||||||||
| Van der Heijden et al. [53] | 6 boys 6 girls |
15.5 | Exercise | 97.0 | 35.3 | 3.0 | 12 wk | 2 times/wk, 60 min/session 2-3 sets, 8–20 reps |
2.6* | 0.8* | 24.0* | Hepatic insulin sensitivity index |
BMI: body mass index; BW: body weight; HOMA-IR: homeostasis model assessment of insulin resistance; IS: insulin sensitivity; OGTT: oral glucose tolerance test; RM: repetition maximum; Δ: Change score.
*Significantly different from baseline within each group (P < 0.05).
†Significantly different from controls or other groups (P < 0.05).