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Boldine prevents kidney damage in diabetic rats. The graph shows the ratio of proteinuria/creatininuria in control (white bar), diabetic (black bar), and diabetic rats treated with 50 mg/Kg/day boldine (grey bar). Each bar represents the mean value ± SEM of 5 different animals. ***P ≤ 0.001, using the one-way ANOVA test followed by Bonferroni's post hoc test.
