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Growth competition experiments between WT and ENF-resistant HIV-1NL4-3 recombinants inoculated at a ratio of 1:1, performed in the presence of ENF (5 μg/ml). Recombinant viruses carrying ENF resistance mutations at gp41 I37T (triangles), V38M (squares), and G36S/V38M (diamonds) were competed against recombinants carrying WT gp41 (circles; A, C, and E, respectively) or against each other (B and D). Recombinants carried hisD or PLAP sequence tags.
