TABLE 5.
Neurologic Sequelae of Culture-Confirmed Pneumococcal Meningitis in Utah Children According to PCV7 Serotype Status
| Sequelaea | PCV7 Serotypes (n = 21)a | Non-PCV7 Serotypes (n = 36)a | P |
|---|---|---|---|
| Cortical blindness | 0 (0) | 6 (17) | .07 |
| Hydrocephalus | 4 (19) | 4 (11) | .4 |
| Institutionalization | 0 (0) | 1 (3) | .5 |
| Microcephaly | 1 (5) | 1 (3) | .7 |
| Quadriplegia | 1 (5) | 6 (17) | .2 |
| Severe developmental delay | 10 (48) | 13 (36) | .6 |
| Persistent seizures at 1 year | 10 (48) | 9 (25) | .08 |
| Ataxia | 3 (14) | 2 (6) | .3 |
| Sensorineural hearing loss | 4 (19) | 13 (36) | .2 |
| Hemiparesis | 5 (24) | 2 (6) | .05 |
| Hyperactivity | 3 (14) | 1 (3) | .09 |
| Cranial nerve palsy | 4 (19) | 9 (25) | .6 |
| Cochlear implant | 2 (10) | 9 (25) | .2 |
| Any neurologic sequelae, including hearing loss and/or behavioral impairment | 16 (76) | 20 (56) | .1 |
Data are presented as n (%).
a
Calculated for survivors with serotyping data available (n = 57).
Neurologic sequelae were diagnosed at discharge and/or follow-up.