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. 2013 Sep;346(3):465–472. doi: 10.1124/jpet.113.205732

Fig. 3.

Fig. 3.

Serum creatinine, BUN, ATN score, and apoptosis in NLRP3−/− mice in cisplatin-induced AKI. Creatinine and BUN were increased in cisplatin-induced AKI (Cis) compared with vehicle-treated (Veh) mice. The creatinine, BUN, ATN score, and number of apoptotic tubular cells were not statistically significantly decreased in NLRP3−/− mice with AKI compared with WT mice with AKI. *P < 0.01 vs. WT Veh; ‡P < 0.01 vs. WT Veh, not statistically significant (NS) vs. WT Cis. The number of animals per group is indicated on the figure. HPF, high-power field.