TABLE 1.

Cytokines in cisplatin-induced and ischemic acute kidney injury

Cytokines	Vehicle WT	Cisplatin WT	Cisplatin NLRP3−/−	Sham WT	Ischemia WT	Ischemia NLRP3−/−
	(n = 3–6)			(n = 4–10)
	pg/mg
IL-1β	4.2 ± 1.1	6.2 ± 0.9	9.6 ± 1.3	4.2 ± 0.7	5.9 ± 0.3	11.4 ± 5.1
IL-6	1.4 ± 0.4	4.0 ± 0.8a	2.0 ± 0.4b	1.9 ± 0.2	9.1 ± 0.2c	22.4 ± 13c
CXCL1	2.4 ± 0.7	112.5 ± 7.2c	98.0 ± 24.5c	7.6 ± 0.8	116 ± 4.7c	107.6 ± 25c
TNF-α	0.3 ± 0.1	1.2 ± 0.1c	1.2 ± 0.1c	0.8 ± 0.2	0.2 ± 0.02	0.5 ± 0.05

^aP < 0.05 vs. vehicle/sham WT.

^bP < 0.05 vs. cisplatin WT.

^cP < 0.01 vs. vehicle/sham WT.