. Author manuscript; available in PMC: 2014 Sep 1.

Published in final edited form as: Semin Nephrol. 2013 Sep;33(5):10.1016/j.semnephrol.2013.07.004. doi: 10.1016/j.semnephrol.2013.07.004

Table 1.

Reported Odds Ratio (Recessive Model) for APOL1-Associated Forms of Nephropathy

Kidney Disease	Clinical Features	Odds Ratio (95% CI)
HIVAN⁹	Collapsing glomerulopathy	29.2 (13.1-68.5)
Idiopathic FSGS⁹	—	16.9 (11.0-26.5)
FGGS with interstitial and vascular alterations¹⁷	All participants in AASK with putative hypertension-attributed nephropathy	2.6 (1.9-3.6)
FGGS with interstitial and vascular alterations¹⁷	AASK participants with eventual increase in serum creatinine level > 3 mg/dL	4.6 (3.1-6.8)
FGGS with interstitial and vascular alterations¹⁷	AASK participants with baseline urine protein: creatinine ratio > 0.6 g/g	6.3 (3.9-10.1)
Nondiabetic ESKD in African Americans¹	Putative hypertension-attributed ESKD (African ancestry)	7.3 (5.6-9.5)
Sickle call nephropathy³¹	Proteinuria	3.4 (not reported)
Lupus nephritis–associated ESKD³⁵	African ancestry	2.4 (1.8-3.3)

Abbreviation: CI, confidence interval.