. Author manuscript; available in PMC: 2014 Sep 1.

Published in final edited form as: Semin Nephrol. 2013 Sep;33(5):10.1016/j.semnephrol.2013.07.004. doi: 10.1016/j.semnephrol.2013.07.004

Table 2.

Kidney Diseases Associated With APOL1 (and MYH9)

Histopathology	Clinical Diagnosis	Population Group (s)	Comments
FSGS	Idiopathic FSGS	African and European	1,2,9
HIV-associated collapsing glomerulopathy	HIV-associated nephropathy	African	9
Nondiabetic ESKD (likely FGGS and FSGS)	Hypertension-attributed ESKD	African and Hispanic	Hispanics from New York City had significant African admixture^1,2
FGGS with arteriolar changes and interstitial fibrosis	Hypertension-attributed nephropathy	African	1,2,17
Sickle cell nephropathy	Sickle cell nephropathy	African	31
Lupus nephritis-associated ESKD	Advanced lupus nephritis with ESKD	African	35
Progressive IgA nephropathy	Advanced IgA nephropathy	Chinese	*MYH9* association¹¹
Diabetic and nondiabetic CKD	Nondiabetic CKD (nonspecific glomerulosclerosis)	European	*MYH9* association^4,5,10

Abbreviation: CKD, chronic kidney disease.