Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Representative reconstructed LC/MS/MS total ion current (TIC) (A) of extracts from a Rat hepatic S9 incubation (+NADPH) of VU0403602, showing the principal metabolites M1 and M2, as well as a minor hydroxylated metabolite M3. A corresponding TIC (B) from the LC/MS/MS analysis (MS/MS, m/z 311) of brain extracts from rats receiving a 30 mg/kg dose (i.p.) of VU0403602 reveals M1 to be the principal hydroxylated metabolite in vivo.
