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Loss of sox9b produces cardiac malformations that resemble those produced by TCDD. Representative brightfield photomicrographs of 96-hpf zebrafish. Lateral views are shown in all images, with head extending leftward, and the yolk sac to the right. Arrowheads denote location of the heart ventricle (V) and atrium (A). AB control and TCDD-treated fish are at left and right, respectively. The center panel shows a sox9bb971 homozygous mutant fish.
