Fig. 4.

All-point histograms of the representative recordings shown in Fig. 3. Burst durations were 5.78, 2.70, 2.63, and 3.92 seconds for the control, mecamylamine, QX-314, and tetracaine bursts, respectively. For clarity of comparisons, the histograms were autoscaled so that the largest components were of the same amplitude. For the QX-314 data, the largest component was the blocked closed state, whereas the largest component was the primary open state in the other histograms.