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. 2013 Sep;84(3):451–458. doi: 10.1124/mol.113.087700

TABLE 1.

The P450 content, protein content, and EROD activities of CYP1B1 ortholog bactosomes

Determined by ferrous CO measurements, the bicinchoninic acid method, and resorufin fluorescence, respectively.


P450 Content
Cytochrome c Reductase Activity
Protein Content
EROD Activity
pmol/mg protein nmol/min/mg protein mg/ml nmol/min/nmol
Human 690 220 10.0 4.30 ± 0.05
Monkey 632 166 17.4 2.6 ± 0.6
Dog 200 1230 10.0 80.0 ± 10
Mouse 220 758 9.1 6.2 ± 0.3
Rat 36 1331 15.1 2.99 ± 0.01
Human (BD)a 153 490 6.5 15.2 ± 0.9
a

Human CYP1B1 Supersomes from BD Biosciences (San Jose, CA) included as a reference point.

HHS Vulnerability Disclosure