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. Author manuscript; available in PMC: 2014 Dec 1.
Published in final edited form as: Leuk Res. 2013 Sep 29;37(12):10.1016/j.leukres.2013.09.024. doi: 10.1016/j.leukres.2013.09.024

Figure 2. D314A and Del20 mutations decrease NPM-RAR binding with RXR.

Figure 2

Figure 2

A. Reticulocyte lysates containing 35S-RXR were incubated with MBP, MBP-NPM-RAR, NPM-NPM-RAR-D314A or MBP-NPM-RAR-del20. Complexes were captured on amylose resin, and separated on 8% SDS-PAGE before autoradiography.

B. Densitometric quantitation of the signal intensity of the bands in Figure 2A (arbitrary units).