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. Author manuscript; available in PMC: 2013 Dec 31.
Published in final edited form as: Biol Blood Marrow Transplant. 2009 Oct 2;16(2):10.1016/j.bbmt.2009.09.023. doi: 10.1016/j.bbmt.2009.09.023

Figure 2.

Figure 2

Pathologic injuries caused by Th1 and Th17 cells. Lethally irradiated BALB/c mice were transplanted with B6 TCD-BM alone or together with Th1 or Th17 cells (1 × 106 each) generated from B6 CD4 T cells. Recipient mice were euthanized and organs were harvested 2–3 weeks after BMT. Formalin-fixed tissues were embedded in paraffin, sectioned, and stained with H&E. (A) Representative micrographs are from liver (upper), intestine (middle), and lung (lower) of BM alone, Th1, or Th17 groups (original magnification ×200). (B) Histopathology was assessed by an expert pathologist in a blind fashion. The data are pooled from 2 replicate experiments with 5 to 7 recipients per group.