Table 5. Associations between ozone-induced plasma neutrophilia with other markers of neutrophilic inflammation in the lung.
| Female subjects | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Male Subjects | Plasma Neut. | BW IL6 | BAL IL6 | pSelectin | ICAM | Epi Neuts. | SM Neuts. | BW Neuts | BAL Neuts | ||
| Plasma Neut. | Pearson Correlation | -.635** | 0.21 | 0.18 | -0.28 | .737** | .600* | -0.33 | 0.20 | ||
| Sig. (2-tailed) | 0.01 | 0.43 | 0.65 | 0.47 | 0.01 | 0.02 | 0.21 | 0.46 | |||
| BW IL6 | Pearson Correlation | 0.27 | 0.27 | -0.27 | 0.20 | -0.60 | -0.45 | .579* | -0.13 | ||
| Sig. (2-tailed) | 0.39 | 0.32 | 0.49 | 0.61 | 0.05 | 0.11 | 0.02 | 0.63 | |||
| BAL IL6 | Pearson Correlation | -0.08 | 0.39 | -0.27 | -0.36 | -0.24 | -0.11 | 0.43 | .603* | ||
| Sig. (2-tailed) | 0.81 | 0.21 | 0.49 | 0.35 | 0.48 | 0.71 | 0.10 | 0.01 | |||
| pSelectin | Pearson Correlation | .820* | 0.27 | 0.15 | .764* | -0.15 | -0.15 | -0.03 | -0.25 | ||
| Sig. (2-tailed) | 0.05 | 0.67 | 0.81 | 0.02 | 0.78 | 0.69 | 0.95 | 0.52 | |||
| ICAM | Pearson Correlation | .945** | 0.46 | 0.04 | 0.69 | -0.29 | -0.23 | -0.02 | -0.15 | ||
| Sig. (2-tailed) | 0.00 | 0.44 | 0.94 | 0.13 | 0.57 | 0.56 | 0.97 | 0.70 | |||
| Epi Neut. | Pearson Correlation | -0.07 | 0.19 | -0.14 | 0.55 | 0.24 | .945** | -0.29 | -0.07 | ||
| Sig. (2-tailed) | 0.83 | 0.55 | 0.66 | 0.26 | 0.65 | 0.00 | 0.40 | 0.85 | |||
| SM Neut. | Pearson Correlation | -0.03 | -0.07 | -0.49 | 0.31 | 0.06 | .699** | -0.23 | -0.15 | ||
| Sig. (2-tailed) | 0.91 | 0.84 | 0.11 | 0.55 | 0.91 | 0.01 | 0.42 | 0.62 | |||
| BW Neut. | Pearson Correlation | 0.41 | .610* | -0.05 | 0.23 | 0.82 | 0.48 | 0.35 | 0.06 | ||
| Sig. (2-tailed) | 0.18 | 0.04 | 0.87 | 0.71 | 0.09 | 0.12 | 0.27 | 0.82 | |||
| BAL Neut. | Pearson Correlation | .635* | 0.17 | -0.14 | -0.17 | 0.01 | -0.01 | -0.34 | 0.30 | ||
| Sig. (2-tailed) | 0.03 | 0.59 | 0.68 | 0.79 | 0.99 | 0.97 | 0.28 | 0.34 | |||
The upper right portion of the matrix presents the associations for the female subjects, with the lower left hand section illustrating the same associations in male volunteers. * P<0.05, ** P<0.01, NS = non significant.