Figure 2. Direction of mitochondrial transport varies depending on frequency of impulse conduction during impulse activity.

(A) The total length of mitochondria transported anterogradely (the sum of the length of all mitochondria transported towards the periphery, µm) was significantly greater in axons stimulated at, or after, 50 Hz (n = 31) (p<0.01; p<0.001), than in resting axons, or in axons stimulated at 1 Hz (n = 30). (B) The relative frequency of long mobile mitochondria (2.5 µm or longer) was higher in axons conducting at high frequency (50 Hz), or at 1 Hz after 50 Hz.