Table 1. Clinical characteristics of patients with APE, CTEPH, and PAS.
Group | APE | CTEPH | PAS | P value@ |
Case number, n | 426 | 156 | 12 | |
Sex (male), n (%) | 239(56.1) | 91(58.3) | 6(50) | 0.7995 |
Age, yrs | 47.1±14.6 | 48.9±13.8 | 45.4±8.8 | 0.3539 |
Normal D-dimer, n (%) | 0(0) | 94(65) | 12(100) | 0.000 |
DVT, n (%) | 426(100) | 92/156(65) | 3/12(25) | 0.000 |
Well score | 7.6±1.81 | 4.6±2.47 | 1.39±1.21 | 0.000 |
Revised Geneva score | 13.1±2.12 | 7.3±3.55 | 4.59±1.90 | 0.000 |
Abnormal hs-CRP, n (%) | 27(6.3) | 12(7.7) | 12(100) | 0.000 |
Abnormal BNP, n (%) | 421(98.8) | 156(100) | 8(66.7) | 0.000 |
Abnormal ESR, n (%) | 25(5.9) | 13(8.3) | 9(75) | 0.000 |
Abnormal LDH, n (%) | 11(2.6) | 8(5.1) | 8(66.7) | 0.000 |
duration of symptoms | 10.3±8.7d | 32.2±26.4 m | 14.6±12.8 m | 0.000 |
Syncope, n (%) | 267(63.7) | 87(55.7) | 9(75) | 0.2048 |
Cough, n (%) | 289(67.8) | 96(61.5) | 8(66.7) | 0.3630 |
Dyspnoea, n (%) | 426(100) | 156(100) | 12(100) | 1 |
Hemoptysis, n (%) | 124(29.1) | 42(26.9) | 3(25) | 0.8439 |
Chest pain, n (%) | 103(24.2) | 31(19.9) | 2(16.7) | 0.4798 |
6MWD, m | — | 326±89 | 289±76 | 0.163* |
WHO function class (III+IV), n (%) | 426(100) | 156(100) | 12(100) | 1 |
DVT: deep vein thrombosis; hs-CRP: high-sensitivity C-reactive protein; BNP: B-type natriuretic peptide; ESR: erythrocyte sedimentation rate; LDH: lactate dehydrogenase; 6MWD: 6-minute walk distance.
@ Comparison among patients with APE, CTEPH, and PAS.
*Comparison between patients with CTEPH and PAS.