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. 2013 Dec 31;8(12):e83200. doi: 10.1371/journal.pone.0083200

Table 1. Clinical characteristics of patients with APE, CTEPH, and PAS.

Group APE CTEPH PAS P value@
Case number, n 426 156 12
Sex (male), n (%) 239(56.1) 91(58.3) 6(50) 0.7995
Age, yrs 47.1±14.6 48.9±13.8 45.4±8.8 0.3539
Normal D-dimer, n (%) 0(0) 94(65) 12(100) 0.000
DVT, n (%) 426(100) 92/156(65) 3/12(25) 0.000
Well score 7.6±1.81 4.6±2.47 1.39±1.21 0.000
Revised Geneva score 13.1±2.12 7.3±3.55 4.59±1.90 0.000
Abnormal hs-CRP, n (%) 27(6.3) 12(7.7) 12(100) 0.000
Abnormal BNP, n (%) 421(98.8) 156(100) 8(66.7) 0.000
Abnormal ESR, n (%) 25(5.9) 13(8.3) 9(75) 0.000
Abnormal LDH, n (%) 11(2.6) 8(5.1) 8(66.7) 0.000
duration of symptoms 10.3±8.7d 32.2±26.4 m 14.6±12.8 m 0.000
Syncope, n (%) 267(63.7) 87(55.7) 9(75) 0.2048
Cough, n (%) 289(67.8) 96(61.5) 8(66.7) 0.3630
Dyspnoea, n (%) 426(100) 156(100) 12(100) 1
Hemoptysis, n (%) 124(29.1) 42(26.9) 3(25) 0.8439
Chest pain, n (%) 103(24.2) 31(19.9) 2(16.7) 0.4798
6MWD, m 326±89 289±76 0.163*
WHO function class (III+IV), n (%) 426(100) 156(100) 12(100) 1

DVT: deep vein thrombosis; hs-CRP: high-sensitivity C-reactive protein; BNP: B-type natriuretic peptide; ESR: erythrocyte sedimentation rate; LDH: lactate dehydrogenase; 6MWD: 6-minute walk distance.

@ Comparison among patients with APE, CTEPH, and PAS.

*Comparison between patients with CTEPH and PAS.