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. 2013 Dec 31;8(12):e83264. doi: 10.1371/journal.pone.0083264

Figure 1. Effects of evodiamine on body weight, food intake, blood parameters and glucose tolerance in KK-Ay mice.

Figure 1

Eight-weeks old female KK-Ay mice were injected i.p. daily with evodiamine (3 mg/kg body weight) or vehicle for 1 week. A, Body weight gain; B, food intake; C, fed glucose level; D, insulin level; E, IPGTT. After starvation for 17 h, mice were injected i.p. with glucose (1.5 mg/g body weight). Data are expressed as mean±SEM; n = 14 and 13 for body weight gain and food intake; n = 8 each for glucose and insulin levels; n = 9 and 8 for IPGTT, in vehicle and evodiamine groups, respectively. *p<0.05, ***p<0.001 vs. vehicle group.