Table 1. Effect of evodiamine on tissue weight in KK-Ay mice.
| Vehicle (n = 5) | Evodiamine (n = 5) | p | |
| Body weight (g) | 38.0±1.2 | 37.3±0.5 | 0.6001 |
| Tissue weight (mg) | |||
| BAT | 251±25 | 236±16 | 0.6305 |
| IWAT | 598±29 | 467±40 | 0.0300 |
| GWAT | 1584±145 | 1283±34 | 0.0786 |
| RWAT | 175±10 | 133±13 | 0.0372 |
| MWAT | 1017±122 | 911±23 | 0.4196 |
| Kidney | 174±7 | 179±6 | 0.5901 |
| Liver | 1901±54 | 1862±80 | 0.6979 |
| Pancreas | 330±21 | 362±17 | 0.2740 |
| Heart | 146±2 | 161±8 | 0.1163 |
| Spleen | 101±9 | 84±7 | 0.1722 |
Female 8-weeks old KK-Ay mice were injected i.p. daily with evodiamine (3 mg/kg body weight) or vehicle control. After 1 week, non-fasting samples of tissues and blood were collected. The left pads of inguinal (IWAT), gonadal (GWAT) and retroperitoneal (RWAT) white adipose tissues were used to measure tissue weight. BAT, brown adipose tissue; MWAT, mesenteric WAT.