Table 3. Top candidates of differentially expressed cell-specific “common” IFN signature genes in patients with SLE and immunized healthy donors.

Affymetrix ID	Gene Symbol	CD4+ T cells (FCa)		CD16− monocytes (FC)		CD16+ monocytes (FC)
		SLEb	Immunized NDc	SLE	Immunized ND	SLE	Immunized ND
216598_s_at	CCL2	NSd	NS	14.6	15.9	NS	NS
209795_at	CD69	NS	NS	27.3	8.7	NS	NS
219895_at	FAM70A	NS	NS	9.2	5.7	15.5	3.8
221345_at	FFAR2	NS	NS	9.8	2.3	10.3	3.6
204187_at	GMPR	NS	NS	10.2	7.4	8.5	5.9
211267_at	HESX1	NS	NS	16.0	10.0	6.4	3.3
202411_at	IFI27	47.1	5.6	37.6	19.4	33.5	15.2
214059_at	IFI44	3.9	5.3	6.9	6.8	10.6	6.3
204439_at	IFI44L	17.7	16.4	13.3	11.2	22.1	17.7
203153_at	IFIT1	14.7	16.1	9.8	10.7	10.2	11.5
204747_at	IFIT3	10.4	12.0	6.1	7.7	4.4	5.6
229450_at	IFIT3	18.1	22.4	6.2	7.2	3.6	4.2
201601_x_at	IFITM1	NS	NS	15.8	9.9	5.3	4.7
214022_s_at	IFITM1	NS	NS	12.2	10.7	5.0	4.2
205569_at	LAMP3	11.0	9.0	NS	NS	NS	NS
200923_at	LGALS3BP	NS	NS	10.9	5.0	NS	NS
226702_at	LOC129607	11.7	9.7	7.0	5.7	6.6	4.7
202145_at	LY6E	20.3	5.0	27.5	8.3	10.3	4.0
202869_at	OAS1	11.4	9.2	3.0	2.9	2.3	2.0
205552_s_at	OAS1	15.1	9.5	3.3	3.0	2.1	2.2
205660_at	OASL	6.2	4.1	11.7	6.9	13.7	8.4
213797_at	RSAD2	12.8	13.2	8.0	11.4	11.3	13.7
242625_at	RSAD2	15.0	12.8	13.4	12.7	14.3	14.3
200986_at	SERPING1	NS	NS	10.2	10.3	15.4	8.6
219519_s_at	SIGLEC1	NS	NS	24.0	16.6	165.0	62.5
44673_at	SIGLEC1	NS	NS	18.7	14.0	26.9	13.2

This table summarizes top candidates of differentially expressed cell-specific “common” IFN signature genes in patients with SLE and immunized healthy donors defined by a fold change ≥10 or ≤−10 in SLE.

^a FC: fold change.

^b Fold change (FC) by the comparison of SLE versus healthy donors (ND) before immunization.

^c FC by the comparison of ND 7 days after immunization with yellow fever vaccine versus ND before immunization.

^d NS: Not significant with cutoff of FC > = 2 or < = −2 in SLE.