Table 2. Comparison of gray matter volumes among the three groups.
Comparison | ||||||
Anatomical region | MNI Coordinate(x, y, z) | Cluster size | F a | S-DUP<HC b | L-DUP<HC c | L-DUP <S-DUP b |
L parahippocampal | −28.5, −22, −20 | 1278d | 9.99 | 4.75 | ||
R parahippocampal | 27, −27, −15 | 1106 | 10.25 | 4.52 | ||
L Fusiform | −37.5, −60, −16.5 | 1278d | 11.67 | 4.33 | 4.57 | 4.28 |
L middle temporal | −54, −4.5, 16.5 | 756 | 7.12 | 4.25 | 3.89 | |
R superior temporal | 59, −31, 1 | 1323 | 13.90 | 5.26 | 3.78 | |
R superior frontal | 30, 62, 0 | 807 | 11.22 | 4.59 |
Abbreviations: L = left, R = right, HC = Healthy Control subjects, S-DUP = short duration of untreated psychosis, L-DUP = long duration of untreated psychosis.
a All effects survived a voxel-wise statistical threshold using ANCOVA controlling for gender, age and years of education (p<0.01, AlphaSim corrected).
b All effects survived a voxel-wise statistical threshold using post-hoc test (p<0.01, AlphaSim corrected).
c All effects survived a voxel-wise statistical threshold using post-hoc test (p<0.05, FDR corrected).
d These peaks belong to the same cluster.