Skip to main content
. 2013 Dec 31;8(12):e83849. doi: 10.1371/journal.pone.0083849

Table 3. Duration of prescription and latent period before onset of SCARs in 25 cases. a .

Prescription duration (days) Latent period (days)
Antiepileptic drugs n Mean ± SD Median (Range) Mean ± SD Median (Range)
All 25 19.3±14.0 15.0 (3–41) 19.1±15.2 16.0 (3–56)
Carbamazepine 10 20.5±14.3 17.0 (3–41) 17.3±15.4 15.0 (3–56)
Gabapentin 7 11.6±11.4 7.0 (3–31) 23.3±19.3 17.0 (4–49)
Phenobarbital 2 16.0±18.4 16.0 (3–29) 14.0±2.8 14.0 (12–16)
Lamotrigine 1 40.0 17.0
Phenytoin 4 29.0±10.5 31.5 (15–38) 22.3±16.5 21.0 (5–42)
Valproate 1 8.0 8.0

Abbreviations; SCARs, severe cutaneous adverse drug reactions; SD, standard deviation

a Cases with prescribed antiepileptic drugs within 60 days of index date.