Table 3. Duration of prescription and latent period before onset of SCARs in 25 cases. a .
Prescription duration (days) | Latent period (days) | ||||
Antiepileptic drugs | n | Mean ± SD | Median (Range) | Mean ± SD | Median (Range) |
All | 25 | 19.3±14.0 | 15.0 (3–41) | 19.1±15.2 | 16.0 (3–56) |
Carbamazepine | 10 | 20.5±14.3 | 17.0 (3–41) | 17.3±15.4 | 15.0 (3–56) |
Gabapentin | 7 | 11.6±11.4 | 7.0 (3–31) | 23.3±19.3 | 17.0 (4–49) |
Phenobarbital | 2 | 16.0±18.4 | 16.0 (3–29) | 14.0±2.8 | 14.0 (12–16) |
Lamotrigine | 1 | 40.0 | 17.0 | ||
Phenytoin | 4 | 29.0±10.5 | 31.5 (15–38) | 22.3±16.5 | 21.0 (5–42) |
Valproate | 1 | 8.0 | 8.0 |
Abbreviations; SCARs, severe cutaneous adverse drug reactions; SD, standard deviation
a Cases with prescribed antiepileptic drugs within 60 days of index date.