FIG. 2.
Alignment of amino acid sequences among DENV-4-specific and cross-reactive Fab monoclonal antibodies. The amino acid sequences of the six chimpanzee Fab monoclonal antibodies recovered by repertoire cloning were compared. (A) Sequences of VL light-chain segments; (B) VH heavy-chain segments. The framework regions (FR1 to FR4) and complementarity-determining regions (CDR1 to CDR3) are shown. A dash indicates where an amino acid deletion occurred, and an identical amino acid is represented by a comma.