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. Author manuscript; available in PMC: 2015 Jan 15.
Published in final edited form as: Transplantation. 2014 Jan 15;97(1):10.1097/TP.0b013e3182a77eba. doi: 10.1097/TP.0b013e3182a77eba

Figure 5.

Figure 5

CM specific immunity results in lower Treg/CD8 ratios despite DST/MR1. AB. Absolute numbers of Foxp3+ CD4+ T cells (A) and CD8+ T cells (B) in spleens of mice obtained 2 weeks after heart transplantation plus DST/MR1 as determined by flow cytometry. C. Calculated ratios of CD8+ cells to Treg for each mouse. D–E. Representative results (D) and quantitative suppression indices (E) of in vitro suppression assays using purified splenic CD25+CD4+Foxp3+ T cells obtained from naïve, CM/CFA immunized or control, OVA/CFA immunized mice 2 weeks after B6 heart transplantation under the cover of DST/MR1. *p<0.05