Table II.
Pain Occurrence by Age, Location, and Genotype
| Diagnosis | ||||
|---|---|---|---|---|
| SC/SB+Thalassemia n (%) |
SS/SB0Thalassemia n (%) |
Total | P-value | |
| 0–12 months of age, N | 32 | 36 | 68 | |
| All SCD pain, n (%) | 7 (21.9) | 14 (38.9) | 21 (30.9) | 0.1890 |
| Any dactylitis, n (%) | 5 (15.6) | 12 (33.3) | 17 (25.0) | 0.1596 |
| 12–24 months of age, N | 43 | 39 | 82 | |
| All SCD pain, n (%) | 11 (25.6) | 20 (51.3) | 31 (37.8) | 0.0227 |
| Any dactylitis, n (%) | 7 (16.3) | 13 (33.3) | 20 (24.4) | 0.1212 |
| 24–36 months of age, N | 42 | 41 | 83 | |
| All SCD pain, n (%) | 12 (28.6) | 24 (58.5) | 36 (43.4) | 0.0079 |
| Any dactylitis, n (%) | 8 (19.0) | 15 (36.6) | 23 (27.7) | 0.0898 |
| 36–48 months of age, N | 34 | 39 | 73 | |
| All SCD pain, n (%) | 15 (44.1) | 26 (66.7) | 41 (56.2) | 0.0624 |
| Any dactylitis, n (%) | 4 (11.8) | 11 (28.2) | 15 (20.6) | 0.1451 |
| 48–60 months of age, N | 28 | 34 | 62 | |
| All SCD pain, n (%) | 12 (42.9) | 23 (67.7) | 35 (56.5) | 0.0721 |
| Anydactylitis, n (%) | 2 (7.1) | 5 (14.7) | 7 (11.3) | 0.4419 |
| 60–72 months of age, N | 22 | 29 | 51 | |
| All SCD pain, n (%) | 12 (54.5) | 22 (75.9) | 34 (66.7) | 0.1401 |
| Any dactylitis, n (%) | 1 (4.5) | 4 (13.8) | 5 (9.8) | 0.3745 |
| 72–84 months of age, N | 17 | 20 | 37 | |
| All SCD pain, n (%) | 8 (47.1) | 13 (65.0) | 21 (56.8) | 0.3309 |
| Any dactylitis, n (%) | 2 (11.8) | 1 (5.0) | 3 (8.1) | 0.5843 |
| 84–96 months of age, N | 13 | 12 | 25 | |
| All SCD pain, n (%) | 5 (38.5) | 9 (75.0) | 14 (56.0) | 0.1107 |
| Any dactylitis, n (%) | 0 | 3 (25.0) | 3 (12.0) | 0.0957 |
Percentages are calculated from the total number of children assessed during the specified age range. P values were obtained from Fisher’s exact test and Kruskal-Wallis test for categorical and continuous variables, respectively.