Table 1.
Demographics and lab characteristics of the study sample, by race/ethnicity and type 2 diabetes status
| Variable | Cases with type 2 diabetes | Non-diabetic controls | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| African American (N=205) | European American (N=185) | P-value | African American (N=93) | European American (N=73) | P-value | |||||||||
| Mean | Median | SD | Mean | Median | SD | Mean | Median | SD | Mean | Median | SD | |||
| Age (years) | 59.84 | 60.39 | 9.62 | 62.9 | 63.59 | 11.00 | 0.0054 | 44.4 | 46 | 11.62 | 45.28 | 47 | 13.84 | 0.4265 |
| Female (%) | 50.00 | 45.00 | 0.391 | 55.00 | 53.00 | 0.8564 | ||||||||
| BMI (kg/m2) | 50.17 | 34.01 | 213.5 | 34.03 | 33.52 | 6.44 | 0.6662 | 31.01 | 30.48 | 7.05 | 27.29 | 25.23 | 6.38 | 0.0006 |
| Diabetes duration (years) | 14.44 | 12.24 | 8.81 | 14.01 | 11.78 | 9.15 | 0.1624 | NA | ||||||
| HbA1c (%) | 7.85 | 7.40 | 1.8 | 7.67 | 7.3 | 1.59 | 0.4309 | 5.79 | 5.7 | 0.72 | 5.46 | 5.5 | 0.29 | <.0001 |
| Serum creatinine (mg/dl) | 1.03 | 0.98 | 0.35 | 0.93 | 0.87 | 0.32 | 0.0002 | 0.88 | 0.85 | 0.19 | 0.88 | 0.86 | 0.16 | 0.7655 |
| MDRD eGFR <60 (%) | 9.00% | 16.00% | 0.039 | 0.00% | 1.00% | 0.259 | ||||||||
| MDRD eGFR (ml/min/1.73 m2) | 87.95 | 87.97 | 20.65 | 82.7 | 83.46 | 22.56 | 0.023 | 104.7 | 107.2 | 14.6 | 88.98 | 88.82 | 16.09 | <.0001 |
| UACR >30 (%) | 34.00% | 34.00% | 0.9938 | 4.00% | 3.00% | 0.5938 | ||||||||
| UACR (mg/g) | 184.7 | 10.11 | 631.3 | 100.9 | 10.98 | 350.4 | 0.9369 | 7.34 | 3.29 | 11.85 | 21 | 3.35 | 127.3 | 0.548 |
SD – standard deviation; BMI – body mass index; HbA1c – hemoglobin A1c; MDRD – Modification of Diet in Renal Disease; eGFR – estimated glomerular filtration rate; UACR – urine albumin:creatinine ratio