TABLE 1.

Pathogen interactions with CD46

Pathogen	Attachment protein	Type of interaction
MV	Hemagglutinin	Binding leads to membrane fusion
Human herpesvirus 6	Glycoprotein H	Binding leads to membrane fusion
Adenovirus (different serotypes)	Knob	Binding results in endocytosis
BVDV	E2a	Probably endocytosis
Neisseria gonorrhoeae and Neisseria meningitides	Pili	Initial attachment, facilitating adhesion
S. pyogenes	Unknown	Unknown

^aTill Ruemenapf, personal communication.