. Author manuscript; available in PMC: 2015 Feb 1.

Published in final edited form as: Biochim Biophys Acta. 2013 Jul 24;1838(2):10.1016/j.bbamem.2013.07.017. doi: 10.1016/j.bbamem.2013.07.017

Table 1.

Binding partners of talin (talin H is 1-433 aa; talin-R is 482-2541 aa; FERM domain is 86-400aa, comprising of F1, F2 and F3 domains; IBS-Integrin Binding site; ABSActin Binding site; DD-Dimerization Domain; aa-amino acids)

Interacting protein	Binding region on talin (amino acid residues)	References
Actin
	ABS-1 (102-435)	[92]
	ABS-2 (951-1327)	[61]
	ABS-3 (2300-2541)	[45], [61], [110], [148], [154]
β-integrin
	IBS-1 (206-435)	[24]
	IBS-2 (1974-2293)	[47], [112], [141], [163], [174]
Talin (full length)	DD (2496-2529)	[45]
Focal adhesion kinase	225-357	[26], [90]
Layilin	280-435	[15], [170]
PIPkinaseɣ 90	308-400	[6], [34], [35]
PIPkinaseɣ 661	150-480	[98]
Phospholipids (acidic)	385-406	[37], [51], [124]
RIAM	655-786 (R2)	[55]
	787-911 (R3)
	1461-1580 (R8)
	1974-2140 (R11)
Smurf1	393-433	[64]
Synemin	1327-1948	[158]
	1359-1659	[46]
Talin F3	1655-1822	[49]
Vinculin	Helices 4,8,9,11,12,27,33,36 ,46,50, 58	[48], [55]