. 2004 May;78(9):4761–4775. doi: 10.1128/JVI.78.9.4761-4775.2004

TABLE 4.

Summary, total, and serotype-specific viremia in cynomolgus monkeys immunized s.c. with one dose of ChimeriVax-DEN1-4 GMP vaccine tetravalent formulations

Group	Dose (log₁₀ PFU)	No. viremic/total no.	Viremia^a
			Mean peak (log₁₀ PFU/ml)		Mean duration (days)
			Total	Serotype	Total	Serotype
1	5,5,5,5	6/6	2.6	D1 = 1.2 (1.5)^b	4.0	D1 = 1.5 (1.8)^b
				D2 = 1.1 (1.6)^b		D2 = 0.8 (1.2)^b
				D3 = 2.3		D3 = 2.3
				D4 = 1.9		D4 = 3.7
2	3,5,5,3	6/6	2.4	D1 = 0	2.5	D1 = 0
				D2 = 1.5 (2.3)^b		D2 = 1.3 (2)^b
				D3 = 1.8 (2.6)^b		D3 = 3 (4.5)^b
				D4 = 0.9 (2.7)^b		D4 = 1.5 (4.5)^b
3	5,5,5,3	6/6	2.1	D1 = 1.2 (1.8)^b	3.0	D1 = 1.5 (2.2)^b
				D2 = 1.4 (1.7)^b		D2 = 2 (2.4)^b
				D3 = 1.8 (2.6)^b		D3 = 2.2 (2.6)^b
				D4 = 1.4 (2.1)^b		D4 = 2.3 (2.8)^b
4	3,3,3,3	6/6	2.5	D1 = 1.2 (1.9)^b	5.5	D1 = 2 (3)^b
				D2 = 1.9		D2 = 3.8
				D3 = 1.6 (2)^b		D3 = 3.5 (4.2)^b
				D4 = 2.5		D4 = 5.3

D1, ChimeriVax-DEN1; D2, ChimeriVax-DEN2; D3, ChimeriVax-DEN3; D4, ChimeriVax-DEN4.

Viremic animals only.