Sequence are denoted by NCBI gi number, which contain NP_065733.2 (Homo sapiens), NP_065602.2 (Mus musculus), XP_508007.2 (Pan troglodytes), NP_543166.1 (Rattus norvegicus), XP_001113391.2 (Macaca mulatta), XP_003409193.1 (Loxodonta Africana), XP_001916919.2 (Equus caballus), DAA14779.1 (Bos taurus), AEJ84245.1 (capra hircus), XP_003359405.1 (Sus scrofa), XP_002913939.1 (Ailuropoda melanoleuca), XP_421735.3 (Gallus gallus), NP_001135714 (Xenopus (Silurana) tropicalis), NP_001139863 (Salmo salar) and 4FS8 (Cyanidioschyzon merolae). The conserved residues are marked in red and the residues Cys32, Cys61, Cys85, Cys156, and Cys206 in hAS3MT are marked with their residue numbers.