Table 1. Clinical characteristics of the 819 unrelated male HBV carriers enrolled in the study.
| ALFs | AsCs (n = 441) | P values § | |||
| LC-ALFs (n = 179) | NLC-ALFs (n = 199) | All ALFs (n = 378) | |||
| Age (years, mean ± SD) | 43.1±12.9 | 39.7±12.3 | 41.3±12.7 | 40.5±10.2 | 0.289 |
| ALT (IU/L, mean ± SD) | 747.5±819.6 | 921.8±816.4 | 842.0±821.2 | 30.0±11.7 | |
| TBil (μmol/L, mean ± SD) | 479.9±194.3 | 476.0±179.2 | 477.7±185.9 | 14.5±5.0 | |
| INR (mean ± SD) | 2.19±0.82 | 2.39±0.93 | 2.29±0.88 | - | |
| HBeAg positive, n (%) | 52 (29.1) | 65 (32.7) | 117 (31.0) | 97 (22.0) | 0.0047 |
| CAG repeat numbers (mean ± SD) | 19.4±2.4 | 19.4±3.0 | 19.4±2.7 | 18.6±3.0 | 0.0002 |
| Alcohol drink, n (%) | 0.969 | ||||
| Never | 112 (62.6) | 113 (56.8) | 225 (59.5) | 262 (59.4) | |
| Occasionally | 26 (14.5) | 53 (26.6) | 79 (20.9) | 102 (23.1) | |
| Mild (<50g/d) | 16 (8.9) | 12 (6.0) | 28 (7.4) | 26 (5.9) | |
| Heavy (≥50g/d and <100g/d) | 10 (5.6) | 7 (3.5) | 17 (4.5) | 16 (3.6) | |
| Problem (≥100g/d) | 15 (8.4) | 14 (7.0) | 29 (7.7) | 35 (7.9) | |
ALFs, HBV-related acute liver failure. AsCs, asymptomatic HBV carriers. LC-ALFs, ALF patients with liver cirrhosis. NLC-ALFs, ALF patients without liver cirrhosis. HBV, hepatitis B virus. HBeAg, hepatitis B virus e antigen. ALT, alanine aminotransferase. TBil, total bilirubin. INR, international normalized ratio for prothrombin time test. SD, standard deviation. §, comparison is conducted between AsCs and ALFs groups, with χ2 tests for HBeAg positive and alcohol drink rates, and student's t-tests for age, HBV DNA and CAG repeat numbers.