Figure 6. Network of dysregulated complexes and influenced proteins.

Dysregulated protein complexes have a downstream effect on other proteins that affect their associations with miRNAs. We identified miRNA-target interactions influenced by the dysregulated protein complexes and then built a network between dysregulated complexes and proteins. Green diamonds represent the components of the dysregulated complexes. Circles represent proteins whose miRNA interactions are influenced by the dysregulated protein. An edge between a circle and a diamond proteins means that the dysregulation of diamond protein have a downstream effect on the ability of miRNAs to target circle proteins. Yellow circle proteins are proteins that are influenced by more than one protein complex.