Table 3. qRT-PCR of differentially regulated angiogenesis and other genes.
Gene name | Gata6 fl/fl | Gata6fl/fl βMHC-Cre | Gata4fl/fl | Gata4fl/fl βMHC-Cre |
Nppa | 1 | 1.26±0.14 | 1 | 0.80±0.11 |
Nppb | 1 | 1.41±0.24 | 1 | 2.33±0.25 |
Atp2a2 | 1 | 1.29±0.15 | 1 | 1.64±0.13 |
Gata4 | 1 | 1.87±0.19 | 1 | 0.25±0.03 |
Zfpm2 | 1 | 1.28±0.13 | 1 | 3.33±0.45 |
Ctf1 | 1 | 1.70±0.18 | 1 | 1.92±0.18 |
Kcne1 | 1 | 0.21±0.06 | 1 | 0.91±0.15 |
Foxc1 | 1 | 2.22±0.26 | 1 | 1.39±0.14 |
Vegf1a | 1 | 0.98±0.10 | 1 | 0.57±0.07 |
Vegfb | 1 | 1.69±0.20 | 1 | 1.52±0.13 |
Vegfc | 1 | 1.52±0.15 | 1 | 1.64±0.14 |
Fgf1 | 1 | 1.06±0.19 | 1 | 1.43±0.19 |
Fgf2 | 1 | 1.43±0.19 | 1 | 1.77±0.20 |
Fgf9 | 1 | 1.46±0.16 | 1 | 1.78±0.22 |
Fgf12 | 1 | 4.77±0.60 | 1 | 1.01±0.10 |
Fgf16 | 1 | 1.74±0.29 | 1 | 0.59±0.08 |
Thbs | 1 | 0.65±0.07 | 1 | 1.12±0.14 |
Timp1 | 1 | 1.75±0.19 | 1 | 2.35±0.38 |
Timp2 | 1 | 1.42±0.14 | 1 | 1.99±0.16 |
Hpse | 1 | 1.33±0.13 | 1 | 1.85±0.19 |
Col15a1 | 1 | 2.24±0.26 | 1 | 1.43±0.11 |
Col18a1 | 1 | 1.36±0.15 | 1 | 1.33±0.13 |
Ctgf | 1 | 3.96±0.57 | 1 | 1.77±0.19 |
Fn1 | 1 | 1.49±0.15 | 1 | 1.82±0.14 |
Adult heart mRNA was collected from the indicated lines of adult mice and subjected to qRT-PCR to analyze for differences in gene expression for the shown set of angiogenesis related genes in the left most column. Values are set relative to expression in Gata6fl/fl or Gata4fl/fl controls.