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. 2013 Dec 31;8(12):e84848. doi: 10.1371/journal.pone.0084848

Table 4. Difference in BP in patients with ESA according to dose.

ESA (units/week) Unadjusted Adjusted1 Adjusted2
SBP (mmHg) 10–2000 ref ref ref
2001–4000 1.0 (−3.3;5.3) 1.2 (−3.1;5.4) 0.7 (−3.6;4.8)
4001–6000 1.3 (−4.2;6.8) 1.7 (−3.8;7.1) 1.2 (−4.3;6.6)
>6000 5.2 (−0.1;10.4) 5.0 (−0.2;10.2) 3.7 (−1.6;9.0)
DBP (mmHg) 10–2000 ref ref ref
2001–4000 0.1 (−2.1;2.3) 0.0 (−2.2;2.2) 0.2 (−2.0;2.4)
4001–6000 0.5 (−2.4;3.3) 0.4 (−2.4;3.3) 0.7 (−2.1;3.6)
>6000 0.5 (−2.3;3.2) 0.5 (−2.2;3.3) 1.1 (−1.7;3.8)

Values are presented as mean difference in blood pressure (with 95% Confidence Interval).

1 Adjusted for age and sex.

2 Adjusted for age, sex, BMI, Diabetes Mellitus, Cardiovascular disease, eGFR.

Abbreviations: ESA = Erythropoiesis-Stimulating Agent, SBP = Systolic Blood Pressure, DBP = Diastolic Blood pressure, ref = Reference, BMI = Body Mass Index, eGFR = estimated Glomerular Filtration Rate.