Table 4. Genotype Frequencies of PARP1 Gene Polymorphism in Breast Cancer Cases below 48 and above 48 years.
| Genotype | Case Parameter | Control | OR | 95% CI | Χ2 | p- value |
|---|---|---|---|---|---|---|
| < 48 Y | ||||||
| Val/Val (wild) | 36 (0.65) | 42 (0.79) | Ref | |||
| Val/Ala | 17 (0.31) | 10 (0.19) | 1.983 | 0.807-4.87 | 2.27 | 0.13215 |
| Ala/Ala (variant) | 2 (0.4) | 1 (0.02) | 2.333 | 0.20-26.80 | 0.49 | 0.48478 |
| Val/Ala + Ala/Ala | 19 (0.35) | 11 (0.21) | 2.015 | 0.848-4.79 | 2.56 | 0.10969 |
| Val | 89 (0.81) | 94 (0.89) | Ref | |||
| Ala | 21 (0.19) | 12 (0.11) | 1.848 | 0.859-3.97 | 2.52 | 0.11256 |
| > 48 Y | ||||||
| Val/Val (wild) | 29 (0.66) | 33 (0.27) | Ref | |||
| Val/Ala | 10 (0.23) | 10 (0.23) | 1.138 | 0.415-3.12 | 0.06 | 0.80167 |
| Ala/Ala (variant) | 5 (0.1) | 0 () | 12.492 | 0.662-235 | 5.24 | 0.02202 |
| Val/Ala + Ala/Ala | 15 (0.24) | 10 (0.23) | 1.707 | 0.665-4.38 | 1.25 | 0.26418 |
| Val | 68 (0.77) | 76 (0.88) | Ref | |||
| Ala | 20 (0.23) | 10 (0.12) | 2.235 | 0.978-5.10 | 3.76 | 0.05264 |