Table 2. Cytokine, oxidative stress and vascular endothelial function in the study population.
CC | CT | TT | P value | |
---|---|---|---|---|
(n=90) | (n=295) | (n=271) | genotype | |
ROS in PBMC | 49.07±20.90 | 35.83±12.52* | 29.98±11.12* # | P < 0.01 |
NOX4 mRNA in PBMC | 0.91±0.31 | 0.52±0.15* | 0.51±0.16* | P < 0.01 |
NOX4 protein in PBMC | 0.49±0.23 | 0.25±0.11* | 0.24±0.12* | P < 0.01 |
HNF3γ mRNA in PBMC | 0.74±0.20 | 0.70±0.23 | 0.72±0.23 | 0.306 |
HNF3γ protein in PBMC | 0.59±0.15 | 0.60±0.16 | 0.60±0.16 | 0.925 |
* P<0.05 vs. CC group; # P<0.05 vs. CT group.