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Effects of NAC on 8-OHdG immunostaining in SHR and control WKY rats. Light micrographs illustrating immunostaining for 8-OHdG in the kidney in control WKY (upper left panel), spontaneously hypertensive rats (SHR) (upper right panel), N-acetylcysteine-treated SHR (SHR + NAC) (lower left panel), and negative control (lower right panel) at 12 weeks of age. Data are representative of 6 independent rats per group with similar trends. Scale bar: 50 μm.
